This book provides a comprehensive and fully referenced description of the serology, inheritance, biochemistry, molecular genetics, and biological significance of human red blood cell antigens and the cell surface structures that carry them. Also detailed are the characteristics of the antibodies which define the blood groups and their clinical significances, particularly as related to the field of transfusion medicine. The book was conceived as a successor to the classic "Blood Groups in Man" by Race and Sanger, and is no less comprehensive. It will be the standard reference for hematologists and geneticists.