Québec’s engagement with the United States is the most significant and consequential point of interaction amongst all its international activities. This new, edited book volume seeks to explore the many ways in which Quebec engages with the United States, including political exchange, border issues, trade, business and investment, transportation, immigration, cultural links and identity, the role of energy transmission and natural resources, and environmental considerations. As a sub-national actor pursuing a wide range of paradiplomatic bilateral and multilateral initiatives directly involving the U.S., our book both explores and explains what, when, why and how Québec has chosen to engage the United States while examining the fundamental issues that lie at the heart of the relationship. Multidisciplinary and interdisciplinary in focus, this edited collection of essays, titled The Québec-United States Relationship: Political, Security, Economic, Environmental and Cultural Dynamics, features the work of scholars who think deeply about Quebec-U.S. relations. Each contribution considers contemporary policy relevant issues; in so doing, this collection examines and emphasizes the background, scope, and impacts of policy decisions. This is an open access book.