Software is the essential enabler for the new economy and science. It creates new markets and new directions for a more reliable, flexible, and robust society. It empowers the exploration of our world in ever more depth. However, software often falls short behind our expectations. Current software methodologies, tools and techniques remain expensive and not yet reliable for a highly changeable and evolutionary market. Many approaches have been proven only as case-by-case oriented methods. This book presents a number of new trends and theories in the direction in which we believe software science and engineering may develop to transform the role of software and science in tomorrow's information society. This publication is an attempt to capture the essence of a new state-of-art in software science and its supporting technology. It also aims at identifying the challenges such a technology has to master.