Originally published in 1928, the preface reads: "It is almost impossible to distinguish between what is ‘elementary’ and what is ‘advanced’ in regard to the nervous system. The constitution and functions of that system are so little matters of common knowledge that it would be safe to assume that practically nothing of its physiology is known to the ordinary reader.

The selection of what is necessary to be known and likely to be comprehended by readers who have no previous knowledge of anatomy and physiology is, therefore, no easy task.

It is certain that in the opinion of some authorities much has been omitted that should have been included; one can but say in self-defence that to have included more than is here considered would have exceeded the limits of a treatise whose title is the A B C." Today it can be read and enjoyed in its historical context.