This book provides a comprehensive introduction to the Institutional Grammar, an approach for analyzing the design of institutions. To lay the foundation for the application of the Grammar for different application areas, the book first provides a background of the IG, before motivating the introduction of an updated version of the Institutional Grammar, called the Institutional Grammar 2.0 that aims at representing institutions more comprehensively and with greater validity. The book then turns to applications and introduces methodological guidance alongside expositions of emerging analytical applications of the “Grammar” that include presentations of current practice, as well as developing novel analytical opportunities that the analyst can apply or build upon for their application. This book is aimed at students, faculty, and practitioners of diverse disciplinary backgrounds with varying levels of understanding of institutional analysis and experience conducting it.