This Safety Guide provides recommendations and guidance on the possible format and content of Safety Analyses Reports (SARs) to be developed in support of requests to regulatory bodies for authorization to construct and/or to operate a nuclear power plant. As such, this Safety Guide recommends how to meet the requirements for preparation of adequate safety demonstrations as established in Safety Standards Series No. GS-R-1, Safety Requirements on Legal and Governmental Infrastructure for Nuclear, Radiation, Radioactive Waste and Transport Safety, and complements Safety Guide No. NS-G-1.2, Safety Assessment and Verification of Nuclear Power Plants.