The 12 full papers and 2 work in progress papers presented together with one keynote talk were carefully reviewed and selected from 28 submissions. The papers discuss the most recent innovations, trends, and experiences in modeling and analysis of complex systems using ITU-T's Specification and Description Language (SDL-2010) and Message Sequence Chart (MSC) notations, as well as related system design languages — including UML, ASN.1, TTCN, SysML, and the User Requirements Notation (URN). SAM 2019’s theme was “Languages, Methods, and Tools for Industry 4.0.”