No lawyer or business operating in North America can escape the significance of NAFTA and its successor, the USMCA agreement of 2018. This Nutshell introduces students, lawyers, government officials and business persons to the law and economics of North American free trade. It first examines the origins, operation and impact of NAFTA 1994. The changes made by the USMCA agreement of 2018, and their implications for business, are explored in detail. In preparing this Nutshell, we have attempted to address the interests not only of North Americans, but also persons located outside the region who are concerned about the externalities of North American free trade, intellectual property and foreign investment law.