This volume consists of articles written by leading scientists in the field of heliospheric physics, analyzing the latest spacecraft measurements and theoretical models related to the solar wind interaction with the Local Interstellar Medium. Particular focus is on the puzzling Voyager cosmic-ray and magnetic field data in the vicinity of the termination shock, and their possible theoretical interpretations. The purposes of future spacecraft missions and modeling issues are also discussed. Topics include: global structure of the outer heliosphere; spacecraft measurements: present and future; galactic and anomalous cosmic rays; shock structure, turbulence and kinetic physics; and remote sensing of the distant heliosphere and Local Interstellar Medium.