This volume gathers the latest advances, innovations, and applications in the field of biosystems engineering, as presented at the 12^th Conference of the Italian Association of Agricultural Engineering (AIIA), held in Palermo, Italy, on September 19-22, 2022. Focusing on the challenges of improving the resilience of agriculture, forestry and food systems in the post-Covid era, it shows how the research has addressed the following topics: Monitoring and modelling hydraulic and hydrological processes in agriculture and forestry systems; Challenges in stream rehabilitation and soil conservation strategies; Sustainable water resource management under climate change scenarios; Planning safe, healthy and resilient territorial, built and green systems; Cultural heritage preservation and rural landscape protection, planning and management; Plant and livestock production processes and technologies. Healthy and Organic farming. Animal welfare; Energy, waste and by-products smart use; Post-harvest logistics and food chain structures technology; Applications and experiences in smart agriculture and forestry; One Health, management and standardization for agriculture and forestry machinery and structures; Big data, machine learning and data hub in biosystems engineering. The contributions were selected by a rigorous peer-review process, and offer an extensive and multidisciplinary overview of the research in the field of biosystems engineering for sustainable agriculture.