Reproduction represents a key point in the maintenance of the pig sector in terms of production and contributes to the establishment of high levels of swine health. Therefore, it is essential to provide valuable tools to veterinarians about the main challenges related to this topic in order to minimise the impact caused by the most important disorders/diseases at reproductive level. This handbook, written by a renowned specialist in this field, has been developed through a visual and practical approach, using numerous figures that illustrate the ovarian pathophysiology of the sow, and providing the suitable content to the veterinarians so as to tackle this matter successfully.