The conformational analysis of six-membered carbocycles and heterocycles is a topic that hasn't been adequately reviewed in about ten years despite a wealth of exciting new developments in the field. The most recent literature on the subject is largely unavailable to the general reader because much of it is scattered in research publications in different areas of chemistry. This multiauthored volume, by international experts, will review the new information which is becoming increasingly important in the organic-, physical organic-, and biochemistry of understanding how conformational effects govern the shapes of molecules and their intermolecular interactions.