Based on empirical brain research from the disciplines of neuroscience, biology, and psychology, Jensen's text explains how the relationship between learning and the brain can impact emotions, patterns, gender, meaningfulness, environments, body rhythms, attitudes, enrichment, and assessment, and how it influences the effects of stress and trauma.

The book's powerful information suggests ways for transforming schools into complete learning organizations by providing students with an optimal learning environment. Implementation of brain-based schooling has proven to increase graduation rates, decrease learning difficulties and discipline problems, and create conditions for the love of learning to flourish.