The thoroughly revised, updated Third Edition of this acclaimed reference retains the goal of the original--a practical, state-of-the-art, superbly illustrated guide to prostate biopsy interpretation. Drs. Epstein and Yang, two leading experts, provide comprehensive, current information on the classification, clinical features, prognosis, and evaluation of difficult and unusual as well as common lesions. Coverage includes normal, inflammatory, tumor-like, benign, and malignant conditions.This edition contains more tables to aid in differential diagnosis of similar lesions. The authors have also added new information on the Gleason grading system...predictive factors on needle biopsy...ancillary studies that can be performed on a needle biopsy...significance of ductal adenocarcinoma on needle biopsy...treatment effect on prostate cancer and its prognostic significance...use of newly described antibodies...the new classification system for stromal tumors of the prostate...and clinical parameters as they relate to needle biopsy findings.A bound-in CD-ROM contains more than 1,700 full-color images--all with detailed legends and 100 with checklists of points in favor of and against a cancer diagnosis.