The CW’s long-running series Supernatural follows the adventures of brothers Sam and Dean Winchester as they pursue the “family business” of hunting supernatural beings. Blending monster-of-the-week storylines with the unfolding saga of the brothers’ often troubled relationship, the show represents Gothic concerns of anxiety, the monstrous, family trauma and, of course, the supernatural. The lines between human and monster, good and evil, are blurred and individual identities and motivations resist easy categorization. This collection of new essays examines how the series both incorporates and complicates Gothic elements related to traditional tropes, storytelling, women and gender issues and monstrosity.