A user's guide to smarter searching of medical information, 'PubMed Essentials' is the complete and concise guide on how to navigate your way through and perfect your use of PubMed. This book explains in detail the general features, the Medical Subject Headings (MeSH), different search strategies, logical filters and how to communicate PubMed records between colleagues. My NCBI is descibed as a powerful alert service with your choice of logical filters and how you build and store your own collection of records in PubMed. Since then this service has developed and its functionality and reliability have improved. Today, PubMed is the most popular database out of this system of NCBI databases. PubMed is the essential tool for health researchers worldwide, handling millions of queries per day.