Wylie 'Coyote' Melville - burnt-out professional therapist and hobbyist forensic consultant - needs a break. South Florida might be home, but it's also home to bad memories and local gangsters bearing grudges. So Wylie and his ace poker-playing best friend Bay Lettique head to the tawdry glitz of Las Vegas to lie low for a while.

But when Wylie and Bay see a woman fall from the balcony of her hotel on the Strip, their low-profile Vegas vacation soon turns into a murder investigation. With the powers-that-be keen to cover up all trace of the woman's death, Wylie starts to follow a trail that leads him across the vast and lawless deserts of redneck Nevada and deep into the heart of a human trafficking conspiracy.

A crime caper filled with Dufresne's trademark black humour, I Don't Like Where This is Going continues the story of Wylie's haphazard investigations into America's bankrupt political system, where power and influence are on sale and the corrupt prey on the innocent.