This book constitutes the refereed proceedings of the 5th International Conference on Digital Human Modeling and Applications in Health, Safety, Ergonomics and Risk Management 2014, held as part of the 16th International Conference on Human-Computer Interaction, HCII 2014, held in Heraklion, Crete, Greece in June 2014, jointly with 13 other thematically conferences. The total of 1476 papers and 220 posters presented at the HCII 2014 conferences were carefully reviewed and selected from 4766 submissions. These papers address the latest research and development efforts and highlight the human aspects of design and use of computing systems. The papers accepted for presentation thoroughly cover the entire field of Human-Computer Interaction, addressing major advances in knowledge and effective use of computers in a variety of application areas. The 65 papers included in this volume are organized in topical sections on modeling posture and motion; anthropometry, design and ergonomics; ergonomics and human modeling in work and everyday life environments; advances in healthcare; rehabilitation applications; risk, safety and emergency.