The history of spin in general, and of the nucleon spin structure in particular, has been full of surprises. For the past 25 years deep inelastic lepton scattering has been studied to determine the carriers of the nucleon spin. However, it was realized only recently that a full understanding of the nucleon spin will also require detailed information on the helicity structure in the resonance region, i.e. in the realm of nonperturbative QCD.This volume gives a status report on the spin structure in the nucleon resonance region, focusing on: new experimental results from SLAC and HERMES; a first glance at the JLab experiments to map out the spin structure functions at low and intermediate four-momentum transfers; the pioneering experiment at MAMI (Mainz) to determine the Gerasimov-Drell-Hearn sum rule for real photons; and recent theoretical concepts and investigations to describe the spin structure in the frameworks of higher twist expansion, phenomenological models and chiral perturbation theory.