The Material Science Handbook was developed to assist nuclear facility operating contractors in providing operators, maintenance personnel, and the technical staff with the necessary fundamentals training to ensure a basic understanding of the structure and properties of metals. The handbook includes information on the structure and properties of metals, stress mechanisms in metals, failure modes, and the characteristics of metals that are commonly used in DOE nuclear facilities. This information will provide personnel with a foundation for understanding the properties of facility materials and the way these properties can impose limitations on the operation of equipment and systems.