Chronic fatigue syndrome - a debilitating disorder associated with fatigue and a range of other constitutional complaints - has been the subject of much controversy in recent years. Originally conceptualized as a persistent viral infection, the disorder is now understood to be a much more complex phenomeon. This acclaimed volume assembles leading experts on CFS form the fields of psychiatry, infectious diseases, general internal medicine, and neuropsychology. Chapters explore the factors that contribute to the development of the disorder and present a multidisciplinary approach to evaluation and clinical management.