This book is a collection of high-quality research papers presented at the International Conference on Smart and Intelligent Systems (SIS 2021), which will be held in Velagapudi Ramakrishna Siddhartha Engineering College (VRSEC), Andhra Pradesh, India, during February 25–26, 2021, in virtual mode. It highlights how recent informatics intelligent systems have successfully been used to develop innovative smart techniques and infrastructure in the field of modern engineering and technology. The book will also be of interest to those working in the field of computational intelligence, smart computer network and security analysis, control and automation system, cloud computing, fog computing and IoT, smart grid communication, smart cities, solar cell synthesis and their performance, green technology, and many more. The contents of this book prove useful to researchers and professionals.