It is critical for non-clinical statisticians to communicate effectively with scientists. Therefore, they must possess the ability to transform scientific questions into statistical hypotheses and models. This book affords both new and experienced statisticians with the opportunity to enhance their statistical tools and improve their consulting skills. It begins by discussing the consulting role of the statistician in drug discovery. It then proceeds to discuss the scientific questions, statistical hypotheses and methodologies, and meaningful tabular and graphical displays used in high-throughput screening, lead-finding animal experiments, drug safety, pharmaceutical science, chemometrics, and genomics.