Ann and Mary Ann are married. They are both neuroscientists and they both witnessed deeply traumatic events when they were young. Now, in the carefully ordered worlds of their marriage and laboratory—which is linked like the two lobes of the brain—Ann and Mary Ann care for, protect, and reflect one another. But when Ann begins to study Fran, a tile artist who is unable to recognize her husband after he commits an unthinkably violent act, Ann and Mary Ann must reckon with what it really means to see and be present to another person. Ann, Fran, Mary Ann is a deeply reflective, reflecting, refracting play about trauma, God, patterns, and the way they live in our bodies, our minds, and acts of love.