These conference proceedings will be of interest to all accelerator scientists and engineers, as well as those concerned with the application of cyclotrons in various fields. The conference covers the latest developments in the science, technology and use of cyclotrons, and includes more than 25 invited talks by specialists in their respective fields. Contributions include papers on newly operating cyclotrons and facilities under construction, compact cyclotrons, cooler rings and post-accelerators, ion sources, beam dynamics, beam diagnostics, cyclotron components, systems and technologies, as well as medical applications — including radiotherapy and radioisotope production — non-medical applications, radioactive beam facilities and new projects and proposals.