While it now attracts many tourists, the Colca Valley of Peru’s southern Andes was largely isolated from the outside world until the 1970s, when a passable road was built linking the valley—and its colonial churches, terraced hillsides, and deep canyon—to the city of Arequipa and its airport, eight hours away. Noble David Cook and his co-researcher Alexandra Parma Cook have been studying the Colca Valley since 1974, and this detailed ethnohistory reflects their decades-long engagement with the valley, its history, and its people. Drawing on unusually rich surviving documentary evidence, they explore the cultural transformations experienced by the first three generations of Indians and Europeans in the region following the Spanish conquest of the Incas.