Volume I of this series is focused on the organization of the eukaryotic cell genome, the mechanisms by which its information is transcribed into RNA and translated into protein and the responses of these processes to external influences such as hormones, mitogens and nutritional changes. Aspects of the sub-cellular organization and distribution of newly synthesized gene products are also considered.The Biochemistry of Cellular Regulation series was conceived with the intention of highlighting certain important areas of research which have made significant contributions to our understanding of how higher cells organize and control their activities. Much of the emphasis in the four volumes which comprise this series is on the responses of cells and tissues to their environments.