This gold-standard practical guide and reference to the safe and effective use of the latest antidepressant medications comprehensively explains in detail the welter of therapeutic options available to frontline physicians who prescribe antidepressants. Single-mindedly concentrating on information of high relevance to their daily clinical use, the authors review the latest developments concerning these medications and demonstrate how experts in the field approach the treatment of depression. Their clinical recommendations cover a wide range of uses in special populations, including geriatric depression, bipolar depression, psychotic depression, substance abuse and depression, HIV/AIDS-related depression, depression associated with pregnancy, post-traumatic stressdisorder, and depression in children. TOC:Biological Theories of Depression and Implications for Current and New Treatments. Clinical Pharmacology and Therapeutics of Antidepressants. Antidepressant Treatment of Geriatric Depression. Treatment of Bipolar Depression. Treatment of Depression in Psychotic Disorders. Substance Abuse and Depression. Depressive Disorders in the Context of HIV/AIDS: Prevalence and Treatment. Diagnosis and Treatment of Depression During Pregnancy and Lactation. Antidepressant Treatments in Posttraumatic Stress Disorder. Antidepressant Therapy in Children and Adolescents: An Overview for the Generalist. Index.