This collection celebrates the 450th year anniversary of the publication of Giorgio Vasari’s Vite (The Lives of the Most Excellent Painters, Sculptors and Architects [Florence: Giunti, 1568]), in which, in the prolegomenon, architects were highly praised along with the principles and technology of architecture. To honor this significant event, the selected articles in this book contain some published excerpts, some revised and expanded, some never published. These articles demonstrate the extraordinary influence of the classical tradition in Renaissance and Mannerist architecture and its role in the education of architectural students. In particular, these essays discuss the materials employed and their functions as well as the architect’s role in society. These articles also address the impact of Mannerist architecture and art theory in sixteenth-century European architecture and culture.