This book presents the proceedings of the KES International Conferences on Innovation in Medicine and Healthcare (KES-InMed-23), held in Rome, Italy, on June 14–16, 2023. Covering a number of key areas, including digital IT architecture in healthcare; advanced ICT for medicine and healthcare; biomedical engineering, trends, research and technologies; and healthcare support systems, this book is a valuable resource for researchers, managers, industrialists and anyone wishing to gain an overview of the latest research in these fields.