This volume contains the Proceedings of the Conference on Interpolation Theory and Applications in honor of Professor Michael Cwikel (Miami, FL, 2006). The central topic of this book is interpolation theory in its broadest sense, with special attention to its applications to analysis. The articles include applications to classical analysis, harmonic analysis, partial differential equations, function spaces, image processing, geometry of Banach spaces, and more. This volume emphasizes remarkable connections between several branches of pure and applied analysis. Graduate students and researchers in analysis will find it very useful.