This book presents a selection of the best papers from the 16th International Conference on Business Excellence, “New Challenges of the Century. Digital Economy and the Green Revolution” (ICBE 2022), held in Bucharest, Romania, in March 2022. Showcasing research findings and perspectives on the new challenges posed by the digital economy and research systems, the book offers valuable insights into the present context of global crisis, together with solutions for the real-world challenges we face today.