For ages, farmers have domesticated plant varieties, while scientists have “made” nature through hybridization and other processes. This give and take—mediated through negotiations, persuasion, the marketplace, and even coercion—has resulted in what we call “nature” and has led to a homogenization of plant crops. Yet homogenization has led to new problems: genetic vulnerability, and the lack of systems to maintain plant germplasm of varieties no longer grown in the fields. This book addresses issues previously viewed as primarily technical concerning the germplasm debate: that is, how, what, and where to store the range of genetic materials necessary to reproduce plants. By examining Brazil, Chile, France, and the United States, the authors show how different cultures respond to the decline in genetic diversity. The findings show that the quest for uniformity in foods, agriculture, and environment eventually threatens everyone. The politicization of this debate is inevitable because the destruction of human cultural diversity goes hand in hand with the destruction of plant varietal diversity. The authors agree that responses to the controversies must involve food security, relinking of food with agriculture and the environment, revaluing traditional knowledge, and rethinking development. They stress that answers will be found not by experts acting unilaterally but through the democratization of scientific and technical exchange.