Meaning means that something is coherently connected. If in life that which has so far been a wonderful match suddenly falls apart, then the last thing is lost. What remains are fragments. The inner connection between world and life is no longer given. The affected person gets into a crisis of meaning. What now appears meaningless and meaningless must be reinterpreted. Those affected are often looking for help and advice. The special issue should give impetus to those active in the field of crisis, suffering and grief and act as a compass.