In presenting this work, it is the attempt of the author to advance the relation of subluxations to disease, also the chiropractic interpretation for the occurrence of many diseases. Appreciating the fact that only rational chiropractic can stand the light of scientific investigation, it is the constant endeavor, in all diseases herein considered, to present the adjusting point, the nerve pathway from the spine to the organ, the physiological action of the adjustment and the chiropractic prognosis. The addition of the medical prognosis is to enable the chiropractic practitioner to draw into play the element of comparison which has as its object the revelation of the efficacy of the practice of chiropractic over the practice of medicine in nearly all instances.