The Leningrad Seminar on mathematical physics, begun in 1947 by V. I. Smirnov and now run by O. A. Ladyzhenskaya, is sponsored by Leningrad University and the Leningrad Branch of the Steklov Mathematical Institute of the Academy of Sciences of the USSR. The main topics of the seminar center on the theory of boundary value problems and related questions of analysis and mathematical physics. This volume contains adaptations of lectures presented at the seminar during the academic year 1989-1990. For the most part, the papers are devoted to investigations of the spectrum of the Schrodinger operator (or its generalizations) perturbed by some relatively compact operator.The book studies the discrete spectrum that emerges in the spectral gaps of the nonperturbed operator, and considers the corresponding estimates and asymptotic formulas for spectrum distribution functions in the large-coupling-constant limit. The starting point here is the opening paper, which is devoted to the important case of a semi-infinite gap. The book also covers the case of inner gaps, related questions in the theory of functions, and an integral equation with difference kernel on a finite interval. The collection concludes with a paper focusing on the classical problem of constructing scattering theory for the Schrodinger operator with potential decreasing faster than the Coulomb potential.