Time and matter are the most fundamental concepts in physics and in any science-based description of the world around us. Quantum theory has, however, revealed many novel insights into these concepts in non-relativistic, relativistic and cosmological contexts. The implications of these novel perspectives have been realized and, in particular, probed experimentally only recently.In the papers in this proceedings, these issues are discussed in a truly interdisciplinary fashion from philosophical and historical perspectives. The leading contributors, including Nobel laureates T W Hänsch and G t' Hooft, address both experimental and theoretical issues.