This issue of Dental Clinics of North America focuses on Orofacial Pain, and is edited by Dr. Steven D. Bender. Articles will include: An Introduction to Orofacial Pain; Clinical Assessment of the Orofacial Pain Patient; Imaging in Orofacial Pain; Musculoskeletal Disorders; Neuropathic Orofacial Pain; Burning Mouth Syndrome; Painful Oral Lesions; The Primary Headaches; Sleep and Pain; Sleep Bruxism; Sex, Gender and Orofacial Pain; Mind-Body Considerations in Orofacial Pain; and more!