For the medical physicist, this book includes detailed discussions on the inverse method, the commissioning and acceptance testing of DMLC, dose calculation, and independent monitor unit (MU) check. For the radiation oncologist and clinical physicist, the relevant material includes treatment planning, quality assurance protocols, disease-specific treatment procedures, and emerging clinical outcome data. In addition, advanced topics relevant to IMRT are addressed such as the estimation of tumor control and normal tissue complication probabilities, the quantification and minimization of treatment uncertainties, the use of respiration-controlled techniques, and the emerging importance of biological imaging.