After losing her sister to a drug overdose, Chief Superintendent Jo Howe is desperate to tackle the world of drugs that consumes the shadowy backstreets of Brighton. Operation Eradicate is her response, deploying undercover tactics to collapse drug circles while also providing treatment services to victims of drug abuse. But not everyone sees this as a positive development .

The man behind Respite pharmaceuticals, billionaire Sir Ben Parsons, views Operation Eradicate as a threat to his business. His colossal empire relies on burgeoning numbers of addicts who survive on their substitute drugs. With connections in the highest levels of government, media and organised crime, Sir Ben unleashes a brutal counterattack on Jo. The question is, how will she survive this fierce onslaught?