This book focuses on applying neuroscience to organizational and managerial contexts, observing its possible applications, present and future potentials, and highlighting the possible criticalities of using neuroscientific paradigms and techniques applied to the management field. Specifically, the first part of the volume aims to offer an overview of how the adoption of an approach and a "neuroscientific mentality" allows to analyse and promote a change, with a view to the promotion of some fundamental components in the organizational context, such as leadership, confident behaviour, business morality and ethics, and stress management. In particular, each of these components is observed through a neuroscientific perspective to offer elements for the promotion of a climate of well-being in the workplace. These aspects are also taken up in the second part of the volume, which focuses mainly on the application of neuroscience to the organizational context, providing evidence on how the use of specific neuroscientific techniques and paradigms, such as those of neuroassessment and neuroenhancement, allows to evaluate and strengthen the executive functions of individuals, to better manage the stress levels and the emotional load of individuals by improving their work performance. In addition to highlighting the impact and effectiveness of some neuroscientific paradigms, the second part of this book highlights the impact of Industry 4.0 on automation and technological developments, such as distance learning in the workplace, from a neuroscientific point of view. Therefore, this book aims to provide a broad overview of how neuroscience within the organisational context allows to fully explore individuals' behaviour by "modifying" it to promote well-being, functional management of stress, and promote a generative climate and encourage trust.