This proceedings volume contains articles from the conference held at Rutgers University in honor of Haim Brezis and Felix Browder, two mathematicians who have had a profound impact on partial differential equations, functional analysis, and geometry. Mathematicians attending the conference had interests in noncompact variational problems, pseudo-holomorphic curves, singular and smooth solutions to problems admitting a conformal (or some group) invariance, Sobolev spaces on manifolds, and configuration spaces. One day of the event was devoted to Einstein equations and related topics. The material is suitable for graduate students and researchers interested in problems in analysis and differential equations on noncompact manifolds.