This volume presents a collection of articles that are based on talks delivered at the International Conference on the Algebraic and Arithmetic Theory of Quadratic Forms held in Frutillar, Chile in December 2007. The theory of quadratic forms is closely connected with a broad spectrum of areas in algebra and number theory. The articles in this volume deal mainly with questions from the algebraic, geometric, arithmetic, and analytic theory of quadratic forms, and related questions in algebraic group theory and algebraic geometry.