This issue of Orthopedics Clinics will survey a broad range of topics across sub-specialty areas on Quality, Value, and Patient Safety in Orthopedic Surgery. Each issue in the series is edited by an experienced team of surgeons from the prestigious Campbell Clinic. Articles in this issue will cover the following topics: Improving Joint Replacement with Continuous Quality Improvement Methods and Tools, Osteolysis as it Pertains to Total Hip Arthroplasty, Perioperative Safety, Pediatric Spine Surgery, Standardization of Care of Common Pediatric Fractures, The volume-value relationship in shoulder arthroplasty, Practicing cost-conscious shoulder surgery, Patient Safety with Driving after Foot and Ankle Surgery, Optimizing Outpatient Total Ankle Replacement from Clinic to Pain Management, The Role of Generic Implants in Orthopaedic Trauma, and The Role of Business Education in the Orthopaedic Curriculum, among others.