With more than 230 million surgical procedures performed annually worldwide, and 30% or more of people affected by chronic pain globally, pain management is consistently a top priority. Its personal and social burden is enormous and thus much literature and research focuses on pain medicine. Along with the evolution of precision medicine, today’s typical pain management strategies include a personalized, multimodal, interdisciplinary treatment approach, which might include pharmacotherapy, psychotherapy, integrative treatments, and invasive procedures. This book presents the latest advancements in pain management, covering a wide field of topics in pain medicine.