Originally presented as lectures, the theme of this volume is that one studies orthogonal polynomials and special functions not for their own sake, but to be able to use them to solve problems. The author presents problems suggested by the isometric embedding of projective spaces in other projective spaces, by the desire to construct large classes of univalent functions, by applications to quadrature problems, and theorems on the location of zeros of trigonometric polynomials. There are also applications to combinatorial problems, statistics, and physical problems.