The global business landscape is changing — rapidly. The past decade has seen major disruptions like the pandemic, military conflict, and geopolitical tension with severe ramifications for multinational organizations that operate as part of the global economy. It is no longer viable to optimize international business activities in tightly coupled value chains too rigid and inflexible to deal with major disruptions, which often happen unexpectedly. Instead, rapidly changing environmental conditions require adaptive processes in agile structures to deal with major events.In this edited volume, researchers at the Copenhagen Business School, associated international scholars, and talented students attempt to make sense of these global political developments, considering how they may affect global business, and how multinational enterprises can navigate this. The volume includes eighteen distinct chapters addressing different business and policy challenges posed by an uncertain economic future. The possible consequences of these changes are described as the increasing deglobalization of markets and firms between Europe and the rest of the world, which will inevitably affect the structure of global industries, and multinational corporations must find ways to deal effectively with the turbulent conditions. Many of the chapters may frame the issues from a European angle, whereas other contributions present extensive backgrounds outside of European markets including China, India, and the United States. So, while the volume presents 'European Perspectives', it also engages with broader economic, political, and cultural views.