Advances in Immunology, Volume 147, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Histone deacetylases as targets in autoimmune and autoinflammatory diseases, The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies, T cells in latent viral infections, Communications of dendritic cells with T cells and NK cells in cancerous tissues, Mechanism and Regulation of Class Switch Recombination by IgH transcriptional Control Elements, IL-2 partial agonist, Preserving Immune Homeostasis with A20, The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies.