In this issue of Primary Care: Clinics in Office Practice, guest editors Drs. Andrew Lutzkanin and Kristen M. Lutzkanin bring their considerable expertise to the topic of Allergy and Immunology. Top experts in the field cover updated treatment strategies for common allergies encountered in primary care, including asthma, food and drug allergies, immunodeficiency, eosinophilic esophagitis, and more.