Delve into the nature and mystery of wisdom in adult education, and what it might mean for the practice of adult education in the complexity of changing times. This issue begins with a look at the nature of wisdom, the wisdom of nature, and how it relates to current issues in the field of adult education. It then looks to neuroscience and the evolution of sacred knowing to explore the connection between learning and wisdom. Covering transcendent and practical wisdom, the issue then draws on Eastern, Western, and Mideastern cultural and religious perspectives to develop a fuller understanding of wisdom. Finally, it covers the aspects of gender and/or culture in relation to wisdom, though in quite different ways. This is the 131st volume of the Jossey-Bass higher education quarterly report series New Directions for Adult and Continuing Education. Noted for its depth of coverage, this indispensable series explores issues of common interest to instructors, administrators, counselors, and policymakers in a broad range of adult and continuing education settings, such as colleges and universities, extension programs, businesses, libraries, and museums.